Fasciculation-cramp syndrome preceding anterior horn cell disease: an intermediate syndrome?
نویسندگان
چکیده
منابع مشابه
Postirradiation localized cramp-fasciculation syndrome.
Radiation plexopathy produces numbness, weakness, and reflex changes.1 Excess motor unit activity (EMUA) after irradiation manifests as myokymia and neuromyotonia in affected muscles.2,3 A 65-year-old woman presented with a pulling sensation in the left axilla and intermittent depression of the left arm of 3 to 4 months duration. Ten months earlier she had completed chemotherapy and radiation t...
متن کاملCramp-fasciculation syndrome in patients with and without neural autoantibodies.
INTRODUCTION We investigated the clinical, electrophysiological and neural autoantibody characteristics in cramp-fasciculation syndrome (CFS) patients. METHODS We reviewed Mayo Clinic records from 2000 to 2011 to identify clinically defined CFS patients who underwent neural autoantibody testing. Stored sera of patients who tested positive for antibodies to voltage-gated potassium channel comp...
متن کاملCramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder.
We report nine patients with muscle aching, cramps, stiffness, exercise intolerance, and peripheral nerve hyperexcitability. Neurologic examination showed calf fasciculations in seven, quadriceps myokymia in two, and deltoid myokymia in one patient. Two patients had mild increase in serum creatine kinase. Muscle biopsy showed either no abnormality (three patients) or mild neurogenic changes (fo...
متن کاملClinical, Electrophysiological, and Serological Evaluation of Patients with Cramp-Fasciculation Syndrome.
INTRODUCTION Cramp-fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability syndrome. There are only a few reports on clinical and serological profile of a CFS cohort that was followed up by a single outpatient clinic. METHODS Clinical, electrophysiological, and serological features of 6 CFS patients (5 men, 1 woman; 27-65 years old) were investigated. RESULTS All patients ...
متن کاملAnterior horn cell dysfunction in Alzheimer's disease.
Electrophysiological studies were undertaken on 29 patients with Alzheimer's Disease. A reduction in the number of functioning motor units was found in the extensor digitorum brevis muscle. The electrophysiological parameters of the motor unit potentials were increased compared to control values. Four of seven muscle biopsies showed abnormalities ranging from mild to severe. The results suggest...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2010
ISSN: 0022-3050
DOI: 10.1136/jnnp.2009.194019